The Ghana College of Physicians and Surgeons was established as a National Postgraduate Medical College for training specialist in medicine, surgery and related disciplines and to provide for related matters by an Act of parliament on the 28th January 2003. Several factions influenced the establishment of the College including a) frustration on the part of the government on the returns on investment put in The West African Postgraduate Medical College (established in 1975), b) high attrition rate of medical practitioners given sponsorship for postgraduate professional training abroad and c) a strong desire to stem braindrain by establishing a national postgraduate training institution. The efforts of ministers for health, health professionals and the Ghana Medical Association accumulated in the setting up of a taskforce chained by Professor George W. Brobby to make recommendations for the establishment of a national postgraduate Medical college in 2000. In 2001 Professor Paul K. Nyame was appointed the Acting Rector of the Ghana Postgraduate Medical Institution with the responsibility of establishing a secretariat for the College. In 2003 the College was finally inaugurated by President J.A Kufuor with Professor Samuel Ofosu-Amaah as the first President and Chairman of Council, Professor Nyame as the Rector and Prof George W. Brobby as Vice Rector. The first group of residents were enrolled in 2004 and graduated in 2007 with the Membership of Ghana College of Physicians and Surgeons.